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Further Medical Problems After a Brain Injury - Fact Sheet

BIAQ LogoIn addition to the commonly encountered medical problems following a brain injury, there are other less customary ones which vigilant families may be able to detect.

Few in this era of cost containment will receive long-term rehabilitation services. Families often become the primary caregivers and need to be alert to various problems and changes that may indicate the need for re-evaluation or follow-up treatment. When the brain is damaged some conditions are readily apparent, such as Coma, loss of speech or motor function. Many other areas - less visibly obvious - are adversely affected and may cause difficulty. Often the individual lacks sufficient communication skills to adequately describe problems and alert the treatment team or family. Additionally, impaired self-awareness may prevent the individual from realising there is a problem. Problems developing after the individual is home and no longer involved in medical or rehabilitation settings may not be as readily recognised as a result of brain injury, and valuable treatment time can be lost if caregivers are unaware of some possible medical consequences of brain injury.

Heterotopic Ossification (HO)

HO is abnormal bone growth within soft tissue at selected joints, most commonly in the hips, shoulders, knees and elbows. It occurs when stem cells within the soft tissue are incorrectly triggered to start producing bone. It usually occurs within the first nine months after injury and is most often discovered by the physical therapist when limited or painful range of motion is seen. However, HO is frequently spotted first by family members who notice swollen or reddish joints or expressions of pain upon being moved.

In general, once HO is confirmed through clinical observation and lab tests, medication is started to retard or slow the growth of the excess bone. There is some recent evidence suggesting that HO can occur as the individual with brain injury ages. This, along with changes in musculoskeletal system problems, such as various forms of arthritis, osteoporosis, and worsening Spasticity (involuntary muscle stiffness) and dystonias (muscle problems causing movement disorders) warns of future problems that must be addressed.

Hearing Loss

Hearing problems can occur for a number of reasons, particularly when the inner ear and/or Temporal Lobes have been damaged. In a traumatic injury the mechanisms of the inner ear may be damaged, or any injury to the brain may include the nerve pathways from the ear, or the regions of the brain responsible for processing sound.

All patients should have an otoscopic examination and hearing screening followed by behavioural testing. External bleeding in the ear canal, middle ear damage, cochlear injury, and/or temporal lobe lesions can cause auditory dysfunction.

Owing to the role of the ear in balance, balance and movement disorders may also occur in people who have impaired hearing following a brain injury.

Visual System Changes

Vision and visual functioning is often impaired following a brain injury. Violent blows to the head can tear the optic nerves running from the eyes to the brain or damage the eyes themselves, and the position of the occipital lobe at the very rear of the brain makes it particularly vulnerable to damage in motor vehicle accidents or assaults. In addition to this, the hospital environment and certain surgical procedures mean that an infection in the eyes is more likely to develop.

The results of an untreated infection of this nature may cause corneal ulcers and other undesirable problems related to the eye. Families who remain vigilant at the bedside are often the first to notice changes in the eyes, such as redness, watering and other signs of a problem. A consultation is usually arranged with an ophthalmologist and with treatment the infection can be brought under control.

Occupational therapists evaluate visual perceptual functioning and teach methods for compensating for any perceptual deficits. In addition, it is important that visual processing and visuomotor ability be evaluated. Some of the more common visual systems problems include double vision, field cuts, sector losses, rapid eye movement and near-sightedness. More complicated problems such as being unable to recognise objects (Agnosia) or even specific classes of objects (such as prosopagnosia: The inability to recognise faces) may also occur.

Due to the eye’s role in informing the brain about the world, clumsiness and other physical problems, including balance disorders and dizziness, can also occur as a result of visual systems changes.

Neuroendocrine Disorders

The Endocrine system refers to communication within the body using hormones made by endocrine glands such as the Hypothalamus, pituitary gland, pineal gland, thyroid, parathyroids, and adrenal glands

The Nervous system refers to the neural collecting, transferring and processing of information between the brain, spinal cord, peripheral nerves, and nerves

The neuroendocrine system refers to the combined workings of these two systems. In other words, “neuroendocrine” covers communication within the body and, therefore, regulation of internal body systems.

At this time, there is very little substantive research information about your risk of developing other medical problems as you age with a brain injury. However research suggests that chronic neuroendocrine difficulties are occurring in women some years post injury.

Five or more years post the injury, women with a brain injury have reported experiencing problems such as weight gain, thyroid disorders, and changes in hair and skin texture and perceived body temperature changes. Other symptoms included chronic sleep disturbances, difficulty controlling blood pressure, a reduction in levels of immunity to infections and arthritic complaints. Damage in the hypothalamus, limbic system and pituitary may play a role in these disturbances.

Treatment for these disorders is usually topical, involving hormone replacement therapy to balance the hormones that the body is no longer producing in the appropriate quantities.

Diabetes Insipidus

Diabetes insipidus is not to be confused with diabetes mellitus, which is the proper name for the condition widely referred to as simply “diabetes”. Diabetes mellitus is characterised by inappropriate blood sugar levels, which are regulated by the hormone insulin which is produced by the pancreas.

Diabetes insipidus is characterised by excessive urination and extreme thirst and involves the action of antidiuretic hormones on the kidneys. Diabetes Insipidus caused by a lack of ADH (antidiuretic hormone, also known as vasopressin) is called central diabetes insipidus. When diabetes insipidus is caused by failure of the kidneys to respond to ADH, the condition is called nephrogenic diabetes insipidus.

Central diabetes insipidus is caused by damage to the hypothalamus or pituitary gland as a result of surgery, infection, tumour, or head injury – potentially, any cause of a brain injury.

Because the cause of this form of diabetes insipidus is a lack of antidiuretic hormone (ADH), treatment is usually with a synthetic hormone called desmopressin.

If treated, diabetes insipidus does not cause severe problems or reduce life expectancy. If not treated, the symptoms are the same as for other forms of diabetes and can include blindness, heart disease and peripheral neuropathy. If diabetes insipidus is severe, the constant flushing of water through the body flushes out sodium, which is required for nerves to function, and in extreme cases can result in a heart attack.

Cerebral Oedema

Swelling of the brain or Cerebral Oedema is a common result of trauma or injury to the brain. Most tissues in the body swell when traumatized. They also require more oxygen to heal. There are some special things about the brain:

  1. It rests inside a bone case, so when it swells, it experiences more trauma;
  2. The more damage the brain receives the more oxygen it needs and the more it swells.

This swelling within the skull results in raised intracranial pressure which can, in addition to causing even more brain damage, result in Hydrocephalus.

Hydrocephalus

Hydrocephalus is a term derived from the Greek words "hydro" meaning water, and "cephalus" meaning head.

Hydrocephalus is commonly known as "water on the brain", although this is not accurate. A watery fluid, known as cerebrospinal fluid or CSF for short, is produced constantly inside each of the four cavities or Ventricles inside the brain. The CSF normally flows through narrow pathways from one ventricle to the next, then out over the outside of the brain and down the spinal cord. The CSF is absorbed into the bloodstream and the amount and pressure are normally kept within a fairly narrow range. If the drainage pathways are obstructed at any point, the fluid accumulates in the ventricles inside the brain, causing them to swell - resulting in compression of surrounding tissue. In babies and infants, the head will enlarge. In older children and adults, the head size cannot increase as the bones, that form the skull, are completely joined together.

The most common way of treating hydrocephalus is by way of shunting. A Shunt is a small pump connected to the ventricular system of the brain and then via a flexible tube diverts the Cerebrospinal fluid into another part of the body, usually the abdominal cavity or a chamber of the heart, where it can be absorbed. A pump (or valve) maintains the CSF at normal pressure within the ventricles.

These shunts are, unfortunately prone to blockages and infections. The shunt failure rate is relatively high and it is not uncommon for patients to have multiple shunt revisions within their lifetime. By 2-3 years of age, approximately half of shunts that have been inserted have failed and been replaced.

Seizures and Epilepsy

A Seizure is a temporary abnormal electro-physiologic phenomenon of the brain, resulting in abnormal synchronization of electrical neuronal activity. It can manifest as an alteration in mental state, tonic or clonic movements, convulsions, and various other psychic symptoms (such as déjà vu – the feeling than an unfamiliar experience has occurred before – or jamais vu – the feeling that a familiar experience has never occurred before) It is caused by a temporary abnormal electrical activity of a group of brain cells. The medical syndrome of recurrent, unprovoked seizures is termed epilepsy, but some seizures may occur in people who do not have epilepsy.

According to American studies, a quarter of all people with moderate to severe brain injury will develop epilepsy.

The following fact sheets at www.braininjury.org.au discuss epilepsy in more depth

Copyright Brain Injury Association of Queensland, Inc, Australia, 2007. This is one of a range of fact sheets made available by the Brain Injury Association of Queensland. While all care has been taken to ensure information is accurate, these fact sheets are only intended as a guide and proper medical or professional advice and information should be sought. The Association will not be held responsible for any injuries or damages that arise from following the information provided in these fact sheets. You can visit the Association’s website at www.braininjury.org.au or send emails to This email address is being protected from spam bots, you need Javascript enabled to view it
 
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Translations on this site are generated automatically by Google and Yahoo. While all care has been taken to ensure information is accurate, the Brain Injury Association of Queensland Inc. will not be held responsible for any injuries or damages that arise from following the information provided on this web site. The translations are dependent on the quality of the translation software and on the language used in this site. Automatic translations by these services cannot be as accurate and proficient as human professional translation.